Missed Breast Cancers on MRI in High-Risk Patients: A Retrospective Case-Control Study

Purpose: To determine if MRI features and molecular subtype influence the detectability of breast cancers on MRI in high-risk patients. Methods and Materials: Breast cancers in a high-risk population of 104 patients were diagnosed following MRI describing a BI-RADS 4-5 lesion. MRI characteristics at the time of diagnosis were compared with previous MRI, where a BI-RADS 1-2-3 lesion was described. Results: There were 77 false-negative MRIs. A total of 51 cancers were overlooked and 26 were...