Mar 24, 2019

The Contribution of Multiparametric Pelvic and Whole-Body MRI to Interpretation of 18F-Fluoromethylcholine or 68Ga-HBED-CC PSMA-11 PET/CT in Patients with Biochemical Failure After Radical Prostatectomy

Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Ur Metser, Sue Chua, Bao Ho, Shonit Punwani, Edward Johnston, Frederic Pouliot, Noam Tau, Asmaa Hawsawy, Reut Anconina, Glenn Bauman, Rodney J Hicks, Andrew Weickhardt, Ian D Davis, Greg Pond, Andrew M Scott, Nina Tunariu, Harbir Sidhu, Louise Emmett
Our purpose was to assess whether the addition of data from multiparametric pelvic MRI (mpMR) and whole-body MRI (wbMR) to the interpretation of ^(18)F-fluoromethylcholine (^(18)F-FCH) or ^(68)Ga-HBED-CC PSMA-11 (^(68)Ga-PSMA) PET/CT (=PET) improves the detection of local tumor recurrence or of nodal and distant metastases in patients after radical prostatectomy with biochemical failure. Methods: The current analysis was performed as part of a prospective, multicenter trial on ^(18)F-FCH or...