Mar 2, 2019
Hyperpolarised 129Xe magnetic resonance imaging to monitor treatment response in children with cystic fibrosis
The European respiratory journal
Pulmonary magnetic resonance imaging using hyperpolarised ^(129)Xe gas (XeMRI) can quantify ventilation inhomogeneity by measuring the percentage of unventilated lung volume (ventilation defect per cent (VDP)). While previous studies have demonstrated its sensitivity for detecting early cystic fibrosis (CF) lung disease, the utility of XeMRI to monitor response to therapy in CF is unknown. The aim of this study was to assess the ability of XeMRI to capture treatment response in paediatric CF...