Oct 19, 2021

Current Concepts in Intracranial Interstitial Fluid Transport and the Glymphatic System: Part I-Anatomy and Physiology

Radiology
Jesse M Klostranec, Diana Vucevic, Kartik D Bhatia, Hans G J Kortman, Timo Krings, Kieran P Murphy, Karel G terBrugge, David J Mikulis
Normal physiologic function of organs requires a circulation of interstitial fluid to deliver nutrients and clear cellular waste products. Lymphatic vessels serve as collectors of this fluid in most organs; however, these vessels are absent in the central nervous system. How the central nervous system maintains tight control of extracellular conditions has been a fundamental question in neuroscience until recent discovery of the glial-lymphatic, or glymphatic, system was made this past decade....