Mi Research - Injury Repair Inflammation

Research Lead: Dr. Andrea Doria61472-doria profile pic.JPG

IRIS stands for I=Injury; R=Repair; I=Inflammation; s=summit

Mission of the IRIs Group:

The goal of our group is to provide support for young investigators to establish their careers nationally and internationally through cross site and interdisciplinary collaboration, research through childhood-adulthood lifespan, basic science-clinical-translational research and data sharing. Ultimately our goal is to enable accomplishments of investigators towards innovation, high quality research and continuous career development.

Research Teams / Imaging Targets in Diseases:

Hypoxia: Childhood sarcomas, Li Fraumeni syndrome

Angiogenesis / Inflammation: Inflammatory bowel disease, juvenile idiopathic arthritis, hemophilic arthritis, morphea, breast cancer, atherosclerosis

List of current MI Discovery Phase Grant funded research projects (Cycle 2015-2016):

“Is repetitive subclinical ischemia the cause of myocardial fibrosis in hypertrophic cardiomyopathy?”

PI: Dr. Andrew Crean

“Dynamic and delayed contrast enhancement on MRE in pediatric inflammatory bowel disease – Pilot study to develop technique to aid distinction of fibrosis from active inflammation”.

PI: Dr. Mary-Louise Greer

“Can neuroimaging MRI feature differentially identify central nervous system vasculitis?”

PI: Dr. Pascal Tyrrell

Educational Activities of the Group:

2015: “Resources for data entry – How to standardize data collection”: Lecturer: Dr. Pascal Tyrrell – November 18, 2015

2016: “Knowledge translation: Can imaging research results be disseminated beyond publications?” – February 10, 2016

Future Plans for the Group:

From 2016 onwards our group plans to continue with periodic multidisciplinary (Radiologists, Clinicians, Epidemiologists, Basic Scientists, Statisticians) seminars on integrated disciplines about topics of interest, including sessions on “Meeting the Scientist” and mentorship for trainees and junior staff.  Identified topics of interest include technology enabled knowledge translation, biomarkers, Grant writing and Excel for dummies. Our group also provides assistance on Science Review of extramural Grant applications of investigators to enable expansion of their investigations typically started with internal resources and seed funding. A seed funding competition through the MI Discovery Phase Grant project is planned for the 2016-2017 cycle.